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Insulin

Insulin Synthesis

The discovery of insulin was one of the greatest events in medical history. The existence of insulin is as necessary as that of glucose (the body's basic unit of fuel). Both of them are related and required for life. In order for the glucose to be regulated, insulin circulates through blood vessels and bind with particular (insulin) receptors, promoting interactions essential for the wellbeing of the body's internal mechanisms.

Insulin is a hormone synthesized exclusively by the pancreatic beta cells. These beta cells are located in the pancreas in clusters known as the islets of Langerhans. Insulin is a small protein produced as part of a larger protein to ensure it folds properly. In the protein assembly of insulin, the messenger RNA transcript is translated into an inactive protein called preproinsulin. Preproinsulin contains an amino-terminal signal sequence that is required in order for the precursor hormone to pass through the membrane of the......


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Approximate Word Count: 771
Approximate Pages: 4 (250 words per double-spaced page)

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