Hemophilia
HEMOPHILIA
Hemophilia is usually an inherited, congenital bleeding disorder characterized by a lack of blood clotting factors, especially factors VIII and IX. It is an X-linked disorder primarily affecting males; females act as carriers. Occurs in 1 in 5,000 males. There is no racial predilection, and hemophilia is found in all ethnic groups.
80% to 85% have factor VIII deficiency or hemophilia A (classic hemophilia).
15% to 20% have factor IX deficiency or hemophilia B (Christmas disease).
Few have factor XI deficiency or hemophilia C.
Transmission of Hemophilia
GENOTYPE OF PARENTS PROBABILITY OF ABNORMALITY IN OFFSPRING
FEMALE MALE
Normal Carrier Hemophiliac......
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