Neurochemistry Of Epilepsy
Neurochemistry of Epilepsy
Epileptic seizures have been described and recognized for millennia. One of the earliest descriptions of a secondarily generalized tonic-clonic seizure was recorded over 3000 years ago in Mesopotamia. The first book about epilepsy was written by Hippocrates about 2500 years ago. His ideas of seizures caused by excessive phlegm and abnormal brain consistency have been rejected, and at the turn of the century, even things such as excessive masturbation was considered a cause of epilepsy. This hypothesis is credited as leading to the use of the first effective anticonvulsants known as bromides (William et al).
In 1929, Berger discovered that electrical brain signals could be recorded from the brain by using scalp electrodes attached to the head, and this discovery led to the use of electroencephalography (EEG) to study and classify epileptic seizures. In 1981, the International League Against Epilepsy (ILAE) developed an international classification of......
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