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Abnormal Pattern Of Brain Development In Premature Babies
Article Date: 02 Aug 2006 - 4:00 PST
Measurement of the way that the brain grows after birth in preterm infants, particularly the relation between brain surface area and cortical volume, may help to predict neurodevelopmental impairment. David Edwards and colleagues from Imperial College London used Magnetic Resonance Imaging to measure brain growth from 23 to 38 wk of gestation in 113 extremely premature infants born between 22 and 29 weeks of gestation. 63 of these children were then assessed to see how they were developing mentally at around 2 years of age. The researchers found that the brain surface area grew faster than the brain volume but that the slower the rate of growth of surface area relative to volume the more likely there was to be delayed development. The more premature babies, and those that were male, were most likely to have a slower growth of the brain surface......
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