Huntington's Disease
Huntington's Disease
Huntington's disease, also known as Huntington's chorea is a genetic disorder
that usually shows up in someone in their thirties and forties, destroys the
mind and body and leads to insanity and death within ten to twenty years. The
disease works by degenerating the ganglia (a pair of nerve clusters deep in the
brain that controls movement, thought, perception, and memory) and cortex by
using energy incorrectly. The brain will starve the neurons (brain cells), and
sometimes make them work harder than usual, causing extreme mental stress. The
result is jerky, random, uncontrollable, rapid movement such as grimacing of the
face, flailing of arms and legs, and other such movement. This is known as
chorea.
Huntington's chorea is hereditary and is caused by a recently discovered
abnormal gene, IT15. IT stands for "interesting transcript" because of the fact
that researchers have no idea what the gene does in the body. Huntington's
disease is an inherited mutation......
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