Gad2 Gene
"GAD2 Identified as Candidate Gene for Obesity" Summary
Obesity is a very hard condition to link to one specific gene because it often runs in families, but their lifestyle habits, as well as genes, contribute to obesity. Also, many genes contribute a small effect to obesity and may differ in different populations. Nuclear families in France were studied to link a candidate gene for obesity by Philippe Froguel and his colleagues. There are many variations in genes from person to person that affect from appearances to diseases, and in most cases of obesity, it is influenced by many genes. Froguel previously linked a region of chromosome 10 and obesity. The GAD2 gene also turned up frequently. GAD2 codes for an enzyme that catalyzes a neurotransmitter to be made that interacts with a neuropeptide that helps stimulate appetite. When screening the subjects and the controls for the GAD2 alleles in the study, Froguel identified one group of alleles as "protective" against......
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