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The disease was first noted in 1786 by Caleb Hillier Parry 1755- 1822, physician from General Hospital, Bath, England. His account was published posthumously in 1825.
However Graves' disease is named after the Irish physician who described several cases in London Medical Journal in 1835. Graves' disease is also known as Parry's disease. In Europe, the disease is known as Basedow's disease. It is the most common cause of thyrotoxicosis (the morbid condition due to over activity of the thyroid gland).

The disorder has three major manifestations:
Hyperthyroidism with diffuse goiter
Ophthalmopathy
and Dermopathy

The three manifestations need not appear together. Indeed one or two never appear, and moreover, the three may run courses that are largely independent of one another.

Graves' disease can occur at any age but is unusual before puberty. It most commonly affects the 30 to 50 year age group. The disease is more frequent in women, the ratio of predominance in women......

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