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By examining where and when genes are expressed in a cell or organism, one can acquire valuable hints to its function, for genes compile the genetic make-up of an organism and exploring the function of genes is helping to uncover the complexity of ourselves and of other forms of life (1). Significant developments have been made in gene monitoring techniques specifically in DNA microarrays which only very recently revolutionized genome expression analysis (1).
Despite continuous improvements and modification to the technique, DNA microarrays are still no more than a glass microscope slide studded with individual immobile nucleotide fragments (1, 2). The fundamentals of DNA microarrays are set on complementary base-pairing (3), and because the exact sequence and position of every segment on the slide is known, each serves as a probe for a specific gene (1).
The two main microarray systems are spotted DNA and oligonucleotide arrays (4); there are others with various difference......

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