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In 1976 scientists at Tate & Lyle Ltd., a large British sugar refiner, and researchers at the University of London discovered sucralose, a no calorie sweetener also known by its brand name as Splenda. Sucralose is a chlorinated chemical compound that is made in a multiple-step chemical manufacturing process. In the process, three atoms of chlorine are substituted for three hydroxyl groups in the sugar molecule sucrose (white table sugar), creating a tightly bonded, highly stable molecule. The tight bonds that hold the molecule together prevent the body from recognizing sucralose as a sugar, therefore preventing it from being metabolized and causing most of it to pass through the body undigested.
Although sucralose has been used outside the United States since 1991, the U.S. Food and Drug Administration (FDA) approved sucralose for use in the U.S. in April of 1998. It took two years for sucralose to become more widespread, and it was not until 2000 that sucralose was used in......

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