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At the path physiologic level, cystic fibrosis (CF) appears to reflect epithelial dysfunction in target organs. (Boucher and Beall) When it comes to scientific studies they have identified defects in the regulation of Tran epithelial ion movements across affected epithelia in this disease that may account for many of the clinical manifestations of this disorder. (Boucher and Beall) They are a possible number of reagents that currently may be available that can assist in these efforts. The reagents can be broken down into two categories: Compounds/ vectors for use primarily in in vitro systems to investigate the basis of cystic fibrosis epithelial defects at the cellular and biochemical level and Compounds/devices that can immediately increase the efficacy of treatment of cystic fibrosis. (Boucher and Beall)
Compounds/ vectors for use primarily in in vitro systems to investigate the basis of cystic fibrosis epithelial defects at the cellular and biochemical level. This topic can......

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