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Xyy Syndrome, Jacob Syndrome

XYY Syndrome, Jacob Syndrome

XYY Syndrome, better known as the Jacob Syndrome is a rare genetic disorder which affects males due to an extra Y chromosome. Healthy males have 46 chromosomes including one X and one Y chromosome. Men with XYY syndrome have 47 chromosomes, two of which are Y chromosomes. It is not known why the extra Y chromosome occurs. The disorder is present at birth and is estimated to occur in one out of every one thousand live births (1). In very rare instances, the syndrome has been passed from father to son, but in most cases heredity cannot be established.
XYY syndrome is a chromosomal condition which occurs only in males and is found with a frequency of 1 in 1,000. A chromosome is a rod-like structure present in the nucleus of all body cells, with the exception of the red blood cells. Chromosomes store genetic information. Normally humans have 23 pairs of chromosomes, 46 chromosomes in total. The 23rd pair, otherwise referred to as the sex chromosomes,......


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