FratFiles

• Save Paper

INFLAMMATION OF THE JOINTS
This auto-immune reaction causes inflammation of the joints, particularly the synovial membrane that lines them. If the process continues, damage to the cartilage and other soft tissue can cause joint deformities.
The effects differ from person to person. Most people first become aware of pain, swelling and stiffness in the small joints of the hands or feet.
So in chronic inflammation, when the antigen is presented on the MHCII of the APC,the Th cell is recognize this and is activated, where it will stimulate other cells in the joint to produce cytokines that are central mediators of the synovial reaction.
It will secrete cytokines(IL-4) to activate the Bcells which will produce the antibodies-IgG and IgM classes which will be deposited in the tissue and will subsequently lead to the activation of serum complement cascade and recruit more phagocytic arm of the immune response which further exacerbate the inflammation of the synovium.
It will also......

View the rest of this paper...

Approximate Word Count: 449
Approximate Pages: 2 (250 words per double-spaced page)

Similar Essays

1. Inflammation Of The Joints
   

   Inflammation Of The Joints INFLAMMATION OF THE JOINTS This auto-immune reaction causes inflammation of the joints, particularly the synovial membrane that lines them. If the

2. Arthrits
   

   Arthrits ARTHRITIS What is arthritis? Arthritis means inflammation of the joints. It causes pain and usually also limits movement of the joints that are affected. There are many

3. Arthritis
   

   Arthritis Arthritis is a general term for approximately 100 diseases that produce either INFLAMMATION of connective tissues, particularly in joints, or noninflammatory

4. Rheumatoid Arthritis
   

   Rheumatoid Arthritis Rheumatoid arthritis is an autoimmune disease that sauses chronic inflammation of the joints. Rhematiod arthritis can also cause inflammation of the tissue

5. Arthritis
   

   Arthritis Arthritis is a disease that causes pain and loss of movement of the joints. The word means joint inflammation. Arth means joint and ritis means inflammation, and